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Search Results for " fgfr 4 "

Targets Recommended: FGFR

18

抑制剂 & 化合物

1

天然产物

1

TargetMol 试剂盒

56

重组蛋白

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Cat. No.	Product Name	Form	Specificity Of Inhibition
CL0084	FGFR inhibitor kit FGFR inhibitor kit

TargetMol 试剂盒

FGFR inhibitor kit

Cat.No: CL0084

Cat. No.	Product Name	Target	Signaling Pathways
TQ0256	FGFR4-IN-1	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	FGFR4-IN-1 是一种 FGFR4 抑制剂 (IC50:0.7 nM)。
T37425	FGFR4-IN-5 FGFR4-IN-5
	FGFR4-IN-5, a covalent FGFR4 inhibitor, demonstrates potency and selectivity with an IC50 value of 6.5 nM. Exhibiting significant in vivo anti-tumor activity, it is applicable for research in hepatocellular carcinoma [1].
T62522	FGFR-IN-4
	FGFR-IN-4 是一种 FGFR 的有效抑制剂。其中成纤维细胞生长因子受体 (FGFR) 是一种与成纤维细胞生长因子配体结合的酪氨酸激酶受体。FGFR-IN-4 具有潜力癌症疾病的研究。
T11280	FGFR4-IN-4	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	FGFR4-IN-4 is a FGFR4 inhibitor with anti-tumor activity.
T73145	FGFR3-IN-4
	FGFR3-IN-4 是一种选择性的 FGFR3抑制剂，IC50值小于 50 nM。FGFR3-IN-4 对 FGFR3的选择性至少比FGFR1高 10 倍。
T63692	FGFR4-IN-7
	FGFR4-IN-7 是共价的、可逆的 FGFR4 抑制剂 (IC50: 0.42 μM)，能够阻断 FGFR4 信号通路，进而诱导细胞凋亡 (apoptosis)。FGFR4-IN-7 能够用于研究肝癌 (HCC)。
T63662	FGFR4-IN-9
	FGFR4-IN-9 是 FGFR4 的选择性抑制剂 (IC50: 75.3 nM)，能够有效抑制肝癌细胞的生长和血管生成。
T79271	FGFR4-IN-14	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	FGFR4-IN-14（Compound 27i）是一种高效的FGFR4抑制剂，IC50值仅为2.4 nM。该化合物能够抑制包含V550L和N535K突变的细胞增殖，且在huh7、BaF3/ETV6-FGFR4-V550L和BaF3/ETV6-FGFR4-N535K细胞系中的IC50分别达到21 nM、2.5 nM和171 nM。在Huh7异种移植模型中，FGFR4-IN-14展现出了明显的抗肿瘤效果，适用于肝细胞癌（HCC）的相关研究。
T63704	FGFR4-IN-11
	FGFR4-IN-11 是选择性的、有效的、共价结合的 FGFR4 抑制剂 (IC50: 2.1 nM)。FGFR4-IN-11 能够明显抑制 FGF19/FGFR4 信号通路，表现出抗癌效果。
T62682	FGFR4-IN-10
	FGFR4-IN-10 (compound 5a) 是一种选择性的、有效的 FGFR4 抑制剂 (IC50: 70.7 nM)。FGFR4-IN-10 不能抑制其他 FGFR 家族成员 (即 FGFR1、FGFR2 和 FGFR3)。
T64015	FGFR4-IN-6
	FGFR4-IN-6 是一种共价的、可逆的 FGFR4 抑制剂 (IC50: 5.4 nM)，表现出良好的口服药代动力学特性。在 Hep3B2.1-7 HCC 细胞系的异种移植小鼠模型中，FGFR4-IN-6 能够明显诱导肿瘤消退，且无明显的毒性。
T73121	FGFR4-IN-8	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	FGFR4-IN-8 (Compound 7v) 是 ATP 竞争性、高选择性的 FGFR4 野生型及其突变体共价抑制剂，对 FGFR4、FGFR4V550L、FGFR4V550M 及 FGFR4C552S 的 IC50 值分别为 0.5、0.25、1.6、931 nM。该化合物能有效抑制 Hep3B 肝细胞癌细胞增殖，显示出显著的抑制效果，具有潜在的临床应用价值。
T79880	FGFR4-IN-16	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	FGFR4-IN-16 (CY-15-2)为FGFR-4选择性共价抑制剂，适用于癌症研究领域。
T27319	FIIN-4 FIIN4	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	FIIN-4 是 FGFR 的共价抑制剂，可用于转移性乳腺癌的研究。
T5473	ASP5878 ASP-5878	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	ASP5878 是一种 FGFR 1 (IC50:0.47 nM)、FGFR 2 (IC50:0.6 nM)、FGFR 3 (IC50:0.74 nM)、和 FGFR 4 (IC50:3.5 nM)的抑制剂，具有口服活性，具有潜在的抗肿瘤作用。
T6836	FIIN-2	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	FIIN2 是一种 FGFR 的不可逆抑制剂，能够抑制 FGFR1 (IC50:3.1 nM)，FGFR2 (IC50:4.3 nM)，FGFR3 (IC50:27 nM) 和 FGFR4 (IC50:45 nM)。
T3726	Erdafitinib 厄达替尼,JNJ-42756493	Apoptosis; FGFR	Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
	Erdafitinib (JNJ-42756493) 是一种喹喔啉衍生物，是一种具有口服活性的FGFR 家族抑制剂，抑制FGFR1/2/3/4活性的IC50分别为1.2、 2.5、3.0和5.7 nM。
T64125	FGFR-IN-8
	FGFR-IN-8 一种高效的、口服具有活力的 FGFR 抑制剂，可抑制野生型和突变型 FGFR。 FGFR-IN-8 能够作用于 FGFR1 (IC50<0.5 nM)、V564F-FGFR2 (IC5016: 189.1 nM)、N549H-FGFR2 (IC50<0.5 nM)、V555M-FGFR3 (IC50: 22.6 nM)、FGFR3 (IC50<0.5 nM) 和 FGFR 4 (IC50: 7.30 nM)。FGFR-IN-8 能够诱导癌细胞凋亡（apoptosis），表现出抗癌效果。

化合物

Cat.No: TQ0256

Target: FGFR

Cat.No: T37425

Synonym: FGFR4-IN-5

Cat.No: T62522

Cat.No: T11280

Target: FGFR

Cat.No: T73145

Cat.No: T63692

Cat.No: T63662

Cat.No: T79271

Target: FGFR

Cat.No: T63704

Cat.No: T62682

Cat.No: T64015

Cat.No: T73121

Target: FGFR

Cat.No: T79880

Target: FGFR

Cat.No: T27319

Synonym: FIIN4

Target: FGFR

Cat.No: T5473

Synonym: ASP-5878

Target: FGFR

Cat.No: T6836

Target: FGFR

Cat.No: T3726

Synonym: 厄达替尼,JNJ-42756493

Target: Apoptosis, FGFR

Cat.No: T64125

Cat. No.	Product Name	Target	Signaling Pathways
T2S0007	Ferulic acid sodium 阿魏酸钠,阿魏酸钠；3-甲氧基-4-羟基肉桂酸钠,Sodium ferulic,Ferulic acid sodium salt,Sodium ferulate	FGFR; Reactive Oxygen Species; 5-HT Receptor; Endogenous Metabolite	Angiogenesis; GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB; Tyrosine Kinase/Adaptors
	Ferulic acid sodium (Sodium ferulic) 是新型的成纤维细胞生长因子受体 1 (FGFR1) 抑制剂。它对于FGFR1和FGFR2的IC50分别为 3.78 and 12.5 μM。

天然产物

Ferulic acid sodium

Cat.No: T2S0007

Synonym: 阿魏酸钠,阿魏酸钠；3-甲氧基-4-羟基肉桂酸钠,Sodium ferulic,Ferulic acid sodium salt,Sodium ferulate

Target: FGFR, Reactive Oxygen Species, 5-HT Receptor, Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00974	FGFR4 Protein, Mouse, Recombinant (His) Fgfr-4,fibroblast growth factor receptor <...	Mouse	HEK293 Cells
	FGFR4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is A0A0R4IZY3.
TMPY-01019	FGFR4 Protein, Mouse, Recombinant (His & hFc) Fgfr-4,fibroblast growth factor receptor <...	Mouse	HEK293 Cells
	FGFR4 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67 kDa and the accession number is A0A0R4IZY3.
TMPK-00379	FGFR4 Protein, Human, Recombinant (His & Avi) CD334,FGFR4,TKF,FGF R4,<...	Human	HEK293 Cells
	FGFR4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22455-1.
TMPK-01322	FGFR4 Protein, Rhesus macaque, Recombinant (His) TKF,JTK2,FGF R4,CD334,FGFR-4<...	Rhesus	HEK293 Cells
	FGFR4 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 39.66 kDa and the accession number is XP_028705775.1.
TMPK-00381	FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated CD334,FGFR-4,FGFR4	Human	HEK293 Cells
	FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22455-1.
TMPK-00380	FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated FGFR4,TKF,FGFR4 β,FGF R<...	Human	HEK293 Cells
	FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.90 kDa and the accession number is P22455-1.
TMPK-00378	FGFR4 beta Protein, Human, Recombinant (His & Avi) JTK2,CD334,FGFR4 β,FGF R4	Human	HEK293 Cells
	FGFR4 beta Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.90 kDa and the accession number is P22455-1.
TMPY-02112	FGFR4 Protein, Human, Recombinant (His) TKF,JTK2,CD334,fibroblast growth factor receptor	Human	HEK293 Cells
	FGFR4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22455-1.
TMPK-00390	FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated FGFR3,JTK4,ACH,FGF R3,FGFR2 α(III...	Human	HEK293 Cells
	FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22607-2.
TMPK-00388	FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi) HSFGFR3EX,FGF R3,ACH,CD333,FGFR2 α(IIIb),J...	Human	HEK293 Cells
	FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22607-2.
TMPK-00385	FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi) FGFR3,EC 2.7.10,FGFR3 β (IIIc),CD333,CEK2,...	Human	HEK293 Cells
	FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 30.1 kDa and the accession number is P22607-1.
TMPK-00389	FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi) FGFR3,FGFR3 β (IIIb),CD333,FGF R3,CEK2,JTK...	Human	HEK293 Cells
	FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 30.5 kDa and the accession number is P22607-2.
TMPK-00386	FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated ACH,CD333,EC 2.7.10,FGFR3 α (IIIc),FGFR3,J...	Human	HEK293 Cells
	FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.1 kDa and the accession number is P22607.
TMPY-00806	FGFR4 Protein, Human, Recombinant (hFc) fibroblast growth factor receptor 4,CD334,...	Human	HEK293 Cells
	FGFR4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66 kDa and the accession number is P22455-1.
TMPY-03322	FGFR4 Protein, Rhesus, Recombinant (hFc) fibroblast growth factor receptor 4	Rhesus	HEK293 Cells
	FGFR4 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.6 kDa and the accession number is XP_001087243.1.
TMPY-02862	FGFR4 Protein, Rat, Recombinant (His) fibroblast growth factor receptor 4	Rat	HEK293 Cells
	FGFR4 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.3 kDa and the accession number is Q498D6.
TMPY-03683	FGFR4 Protein, Rhesus, Recombinant (His) fibroblast growth factor receptor 4	Rhesus	HEK293 Cells
	FGFR4 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.8 kDa and the accession number is XP_001087243.1.
TMPY-02635	FGFR4 Protein, Rat, Recombinant (hFc) fibroblast growth factor receptor 4	Rat	HEK293 Cells
	FGFR4 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66 kDa and the accession number is Q498D6.
TMPK-00391	FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated HSFGFR3EX,FGFR3,FGF R3,ACH,CD333,FGFR<...	Human	HEK293 Cells
	Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell p...
TMPK-00384	FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi) CD333,EC 2.7.10,JTK4,FGFR3 α (IIIc),FG...	Human	HEK293 Cells
	FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.1 kDa and the accession number is P22607.
TMPK-00686	FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His) CEK,CD333,HSFGFR3EX,FGFR3,FGF R3,FGFR<...	Mouse	HEK293 Cells
	FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.09 kDa and the accession number is E9QNJ9.
TMPK-00387	FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated HSFGFR3EX,FGF R3,EC 2.7.10,CD333,FGFR3 β (...	Human	HEK293 Cells
	Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell p...
TMPY-06037	FGFR4 Protein, Human, Recombinant (His), Biotinylated CD334,TKF,JTK2,fibroblast growth factor receptor	Human	HEK293 Cells
	FGFR4 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22455-1.
TMPJ-00842	FGF-2 Protein, Rat, Recombinant bFGF,Heparin-Binding Growth Factor 2,FGFB,Fibroblast Growth ...	Rat	E. coli
	FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. They act on several cell types to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects, and tissue repair. FGF-basic is a non-glycosylated heparin binding g...
TMPJ-00715	FGF-19 Protein, Human, Recombinant (His) FGF-19,Fibroblast growth factor 19,FGF19	Human	E. coli
	Fibroblast growth factor 19 (FGF19) is a secreted protein which belongs to the FGFs family. FGF19 is expressed in fetal brain, cartilage, retina, and adult gall bladder. FGFs modulate cellular activity via at least 5 distinct subfamilies of high-affinity FGF receptors (FGFRs): FGFR-1, -2, -3, and -4, all with intrinsic tyrosine kinase activity. FGFRs can be important for regulation of glucose and lipid homeostasis. FGF19 has important roles as a hormone produced in the ileum in response to bile ...
TMPY-00749	FGF-2 Protein, Human, Recombinant fibroblast growth factor 2 (basic),FGF-2,FGFB,HBGF-2,BFGF	Human	E. coli
	FGF-2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16.5 kDa and the accession number is P09038-4.
TMPJ-00864	VEGF165 Protein, Human, Recombinant Vascular Endothelial Growth Factor Isoform 165,血管内皮生长因子,VEGF...	Human	HEK293 Cells
	Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator in vasculogenesis and angiogenesis both physiologically and pathologically. VEGF-A has 8 differently spliced isoforms, of which VEGF165 is the most abundant one. VEGF165 is a disulfide-linked homodimer consisting of two glycosylated 165 amino acid polypeptide chains. VEGF stimul...
TMPK-00823	VEGF165 Protein, Human, Recombinant (His & Avi) 血管内皮生长因子,RP1-261G23.1,MVCD1,MGC70609,VEGFA,VEGFMGC70609,VPF,...	Human	HEK293 Cells
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF165 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 22.2 kDa and the accession number is P15692-4.
TMPY-04911	VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated vascular endothelial growth factor A,血管内皮生长因子	Human,Cynomolgus	HEK293 Cells
	VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 23.1 kDa and the accession number is P15692-4.
TMPY-02893	NT5C3A/NT5C3 Protein, Human, Recombinant P5N1,P5N-1,hUMP1,NT5C3,cN-III,PSN1,UMPH1,UMPH,POMP,5'-nucleo...	Human	E. coli
	NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. NT5C3A expression required both an intronic IFN-stimulated response element and the IFN-stimulated transcription factor IRF1. Overexpression of NT5C3A, but...
TMPK-00424	CD45 Protein, Human, Recombinant (His & Avi), Biotinylated LCA,LY5,EC 3.1.3.48,CD45,L-CA,T200,CD4...	Human	HEK293 Cells
	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. CD45 Protein, Human, Recombinant (His & Avi...
TMPK-00822	VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled RP1-261G23.1,VEGFA,MGC70609,VEGF,VEGFMGC70609,VPF,VAS,MVCD1,...	Human	HEK293 Cells
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 22.2 kDa and the accession number is P15692-4.
TMPY-04471	APEG1 Protein, Human, Recombinant (His) SPEG complex locus,BPEG,SPEGalpha,SPEGβ,APEG-1,SPEGbeta,APEG...	Human	E. coli
	Striated muscle preferentially expressed protein kinase, also known as aortic preferentially expressed protein 1, APEG-1, SPEG and KIAA1297, is a protein that belongs to the protein kinase superfamily and CAMK Ser/Thr protein kinase family. SPEG / APEG-1 contains two fibronectin type-III domains, nine Ig-like (immunoglobulin-like) domains, two protein kinase domains. Isoform 1 of SPEG is preferentially expressed in striated muscle. Non-kinase form such as isoform 3 of SPEG is predominantly expre...
TMPK-00423	CD45 Protein, Human, Recombinant (His & Avi) CD45R,LY5,EC 3.1.3.48,B220,CD45,T...	Human	HEK293 Cells
	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. CD45 Protein, Human, Recombinant (His & Avi...
TMPJ-01333	TEM8/ANTXR1 Protein, Human, Recombinant (His) ATR,ANTXR1,TEM8,Tumor Endothelial Marker 8,Anthrax Toxin Rec...	Human	HEK293 Cells
	Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It ...
TMPY-05598	Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated SIGLEC2,SIGLEC-2,CD22 molecule	Human	HEK293 Cells
	Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 103.7 kDa and the accession number is P20273-4.
TMPJ-00782	Amyloid Precursor Protein, Human, Recombinant (hFc) Amyloid Precursor,Amyloid Precursor Protein 695,APP695	Human	HEK293 Cells
	Amyloid precursor protein (APP) is a type I membrane protein with several isoforms due to alternative splicing, performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Of the three major splice isoforms of APP (APP695, APP751, and APP770) APP695 is the predominant neuronal form from which Amyloid beta peptide and transcriptionally-active cleaved intracellular domain of APP (AICD) are preferentially generated by selective process...
TMPY-04754	CASK Protein, Human, Recombinant CMG,LIN2,MRXSNA,CAMGUK,calcium/calmodulin-dependent serine p...	Human	Baculovirus Insect Cells
	CASK Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 102.1 kDa and the accession number is O14936-4.
TMPY-00225	CLEC9A Protein, Mouse, Recombinant (hFc) C-type lectin domain family 9, member A,9830005G06Rik,DNGR-1	Mouse	HEK293 Cells
	CLEC9A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.1 kDa and the accession number is Q8BRU4-4.
TMPY-01117	MRAP Protein, Human, Recombinant (hFc) FALP,FGD2,melanocortin 2 receptor accessory protein,GCCD2,B2...	Human	HEK293 Cells
	MRAP (Melanocortin 2 Receptor Accessory Protein) is a Protein Coding gene. This gene encodes a melanocortin receptor-interacting protein. It belongs to the MRAP family. MRAP, which contains a single transmembrane domain, has a unique structure, an antiparallel homodimer. MRAP is a single transmembrane domain accessory protein and a critical component of the hypothamo pituitary-adrenal axis. MRAP is highly expressed in the adrenal gland and is essential for adrenocorticotropin hormone (ACTH) rece...
TMPJ-00233	CD200R1/CRTR2 Protein, Human, Recombinant (His) Cell Surface Glycoprotein CD200 Receptor 1,OX2R,MOX2R,CD200 ...	Human	HEK293 Cells
	Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. CD200R1 and CD200 associate via their respective N-terminal Ig-like domains. CD200R1 is restricted primarily to mast cells, basophils, macrophages, and dendritic cells. It propagates inhibitory signals despite its lacking a cytopla...
TMPK-00702	ANTXR2 Protein, Human, Recombinant (His) cI-35,Antxr2,JHS,CMG-2,CMG2,JHF,HFS,ISH	Human	HEK293 Cells
	The Capillary Morphogenesis Gene 2 (CMG2) gene encodes an Anthrax toxin receptor (ANTXR2),ANTXR2/CMG2 was originally identified as a result of up-regulation during capillary morphogenesis of endothelial cells (ECs) cultured in vitro. ANTXR2/CMG2 functions to promote endothelial proliferation and morphogenesis during sprouting angiogenesis, consistent with the endothelial expression of ANTXR2/CMG2 in several vascular beds.
TMPY-01033	IL-32 Protein, Human, Recombinant (isoform alpha, His) IL-32δ,IL-32beta,IL32,TAIFc,IL-32γ,白介素,IL-32 Protein(isoform...	Human	HEK293 Cells
	IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathways. It is regulated robustly by other major proinflammatory cytokines and is crucial to inflammation and immune responses. Four of the IL-32 isoforms (alpha, beta, gamma, and delta) are the most representative IL-32 transcripts, and the gamma isoform of IL-32 is the most active,...
TMPY-01823	PTK9 Protein, Human, Recombinant MGC41876,twinfilin actin binding protein 1,A6,MGC23...	Human	E. coli
	PTK9 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 29 kDa and the accession number is Q12792-4.
TMPY-00119	FLT1 Protein, Human, Recombinant (hFc) VEGFR1,VEGFR-1,fms-related tyrosine kinase 1,FLT-1,FLT	Human	HEK293 Cells
	FLT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.1 kDa and the accession number is P17948-4.
TMPY-04563	CASK Protein, Human, Recombinant (His & GST) calcium/calmodulin-dependent serine protein kinase (MAGUK fa...	Human	Baculovirus Insect Cells
	CASK Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 130 kDa and the accession number is O14936-4.
TMPJ-01256	Caspase-10 Protein, Human, Recombinant (His) CASP10,FAS-Associated Death Domain Protein Interleukin-1B-Co...	Human	E. coli
	Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granzyme B and autocatalytic activity generate the two active subunits: Caspase-10 subunit p23/17, Caspase-10 subunit p12. Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the execution-phase of cell apoptosis, the initiation and execution. Human ca...
TMPY-01822	PTK9 Protein, Human, Recombinant (His & GST) PTK9,MGC41876,A6,MGC23788,twinfilin actin binding p...	Human	E. coli
	PTK9 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 57 kDa and the accession number is Q12792-4.
TMPY-04565	SRPK3 Protein, Human, Recombinant (His & GST) MSSK1,MGC102944,STK23,MSSK-1,SRSF protein ...	Human	Baculovirus Insect Cells
	Serine / threonine-protein kinase SRPK3, also known as Muscle-specific serine kinase 1, Serine/arginine-rich protein-specific kinase 3, SR-protein-specific kinase 3, Serine / threonine-protein kinase 23, MSSK-1, SRPK3 and MSSK1, is a member of the protein kinase superfamily and CMGC Ser / Thr protein kinase family. SRPK3 is a protein kinase belonging to serine/arginine protein kinases (SRPK) family, which phosphorylates serine / arginine repeat-containing proteins, and is controlled by a muscle-...
TMPJ-01188	CORO6 Protein, Human, Recombinant (His) Coronin-6,Clipin-E,CORO6	Human	E. coli
	Coronin 6, a newly identified member of the coronin family, is highly enriched at adult NMJs and regulates AChR clustering via modulating the interaction between receptors and the actin cytoskeletal network. Coronins are a family of conserved actin-binding proteins originally identified in the actin-rich structure of the amoeba Dictyostelium discoideum . To date, seven members of coronins have been identified in mammals, and most exhibit tissue-specific distribution patterns. Coronin 6 is promin...
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重组蛋白

FGFR4 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00974

Species: Mouse

Expression System: HEK293 Cells

FGFR4 Protein, Mouse, Recombinant (His & hFc)

Cat.No: TMPY-01019

Species: Mouse

Expression System: HEK293 Cells

FGFR4 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00379

Species: Human

Expression System: HEK293 Cells

FGFR4 Protein, Rhesus macaque, Recombinant (His)

Cat.No: TMPK-01322

Species: Rhesus

Expression System: HEK293 Cells

FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00381

Species: Human

Expression System: HEK293 Cells

FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00380

Species: Human

Expression System: HEK293 Cells

FGFR4 beta Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00378

Species: Human

Expression System: HEK293 Cells

FGFR4 Protein, Human, Recombinant (His)

Cat.No: TMPY-02112

Species: Human

Expression System: HEK293 Cells

FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00390

Species: Human

Expression System: HEK293 Cells

FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00388

Species: Human

Expression System: HEK293 Cells

FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00385

Species: Human

Expression System: HEK293 Cells

FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00389

Species: Human

Expression System: HEK293 Cells

FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00386

Species: Human

Expression System: HEK293 Cells

FGFR4 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00806

Species: Human

Expression System: HEK293 Cells

FGFR4 Protein, Rhesus, Recombinant (hFc)

Cat.No: TMPY-03322

Species: Rhesus

Expression System: HEK293 Cells

FGFR4 Protein, Rat, Recombinant (His)

Cat.No: TMPY-02862

Species: Rat

Expression System: HEK293 Cells

FGFR4 Protein, Rhesus, Recombinant (His)

Cat.No: TMPY-03683

Species: Rhesus

Expression System: HEK293 Cells

FGFR4 Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-02635

Species: Rat

Expression System: HEK293 Cells

FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00391

Species: Human

Expression System: HEK293 Cells

FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00384

Species: Human

Expression System: HEK293 Cells

FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00686

Species: Mouse

Expression System: HEK293 Cells

FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00387

Species: Human

Expression System: HEK293 Cells

FGFR4 Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-06037

Species: Human

Expression System: HEK293 Cells

FGF-2 Protein, Rat, Recombinant

Cat.No: TMPJ-00842

Species: Rat

Expression System: E. coli

FGF-19 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00715

Species: Human

Expression System: E. coli

FGF-2 Protein, Human, Recombinant

Cat.No: TMPY-00749

Species: Human

Expression System: E. coli

VEGF165 Protein, Human, Recombinant

Cat.No: TMPJ-00864

Species: Human

Expression System: HEK293 Cells

VEGF165 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00823

Species: Human

Expression System: HEK293 Cells

VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-04911

Species: Human,Cynomolgus

Expression System: HEK293 Cells

NT5C3A/NT5C3 Protein, Human, Recombinant

Cat.No: TMPY-02893

Species: Human

Expression System: E. coli

CD45 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00424

Species: Human

Expression System: HEK293 Cells

VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled

Cat.No: TMPK-00822

Species: Human

Expression System: HEK293 Cells

APEG1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04471

Species: Human

Expression System: E. coli

CD45 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00423

Species: Human

Expression System: HEK293 Cells

TEM8/ANTXR1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01333

Species: Human

Expression System: HEK293 Cells

Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPY-05598

Species: Human

Expression System: HEK293 Cells

Amyloid Precursor Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00782

Species: Human

Expression System: HEK293 Cells

CASK Protein, Human, Recombinant

Cat.No: TMPY-04754

Species: Human

Expression System: Baculovirus Insect Cells

CLEC9A Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-00225

Species: Mouse

Expression System: HEK293 Cells

MRAP Protein, Human, Recombinant (hFc)

Cat.No: TMPY-01117

Species: Human

Expression System: HEK293 Cells

CD200R1/CRTR2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00233

Species: Human

Expression System: HEK293 Cells

ANTXR2 Protein, Human, Recombinant (His)

Cat.No: TMPK-00702

Species: Human

Expression System: HEK293 Cells

IL-32 Protein, Human, Recombinant (isoform alpha, His)

Cat.No: TMPY-01033

Species: Human

Expression System: HEK293 Cells

PTK9 Protein, Human, Recombinant

Cat.No: TMPY-01823

Species: Human

Expression System: E. coli

FLT1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00119

Species: Human

Expression System: HEK293 Cells

CASK Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04563

Species: Human

Expression System: Baculovirus Insect Cells

Caspase-10 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01256

Species: Human

Expression System: E. coli

PTK9 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-01822

Species: Human

Expression System: E. coli

SRPK3 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04565

Species: Human

Expression System: Baculovirus Insect Cells

CORO6 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01188

Species: Human

Expression System: E. coli

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